Vietnam: What are the regulations on specific treatment regimen for patients infected with Genital Herpes Simplex virus?

Regarding the guidance on the diagnosis and treatment of Genital Herpes Simplex, what are the regulations on specific treatment regimen for patients infected with Genital Herpes Simplex virus?

Under Sub-section 3.2, Section 3 of the Guidelines for Diagnosis and Treatment of Herpes Simplex (Promulgated with Decision 5183/QD-BYT in 2021), the specific treatment regimen for patients infected with Genital Herpes Simplex virus in Vietnam is prescribed as follows:

 

Adolescents, Adults, and Pregnant Women

HIV-Infected and Immunocompromised Individuals

Primary Genital Herpes

• Aciclovir 400 mg orally 3 times/day for 10 days (standard dose)

• Aciclovir 200 mg orally 5 times/day for 10 days

• Valaciclovir 500 mg orally 2 times/day for 10 days

• Famciclovir 250 mg orally 3 times/day for 10 days

Recurrent Genital Herpes

Treatment should commence within 24h from the onset of symptoms

• Aciclovir 400 mg orally 3 times/day for 5 days, or 800 mg orally 2 times/day for 5 days, or 800 mg orally 3 times/day for 2 days

• Valaciclovir 500 mg orally 2 times/day for 3 days

• Famciclovir 250 mg orally 2 times/day for 5 days

• Aciclovir 400 mg orally 3 times/day for 5 days

• Valaciclovir 500 mg orally 2 times/day for 5 days

• Famciclovir 500 mg orally 2 times/day for 5 days

Prophylactic Treatment

For patients with 4-6 recurrences/year or more.

• Aciclovir 400 mg orally 2 times/day daily, for 6-12 months

• Valaciclovir 500 mg orally 1 time/day daily, for 6-12 months

• Famciclovir 250 mg orally 2 times/day daily, for 6-12 months

• Aciclovir 400 mg orally 2 times/day daily, for 6-12 months

• Valaciclovir 500 mg orally 2 times/day daily, for 6-12 months

• Famciclovir 500 mg orally 2 times/day daily, for 6-12 months

Adjunct local treatment: saline rinses, and topical anesthetics such as lidocaine. Topical Aciclovir is less effective.

Respectfully!

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