The Ministry of Health guides the treatment of intestinal Strongyloidiasis in Vietnam: Contraindications to Albendazole for pregnant women in the first 3 months?
- What is the treatment principle for intestinal strongyloidiasis (Strongyloidiasis) in Vietnam?
- Guidelines for specific treatment of strongyloidiasis in Vietnam in 2022?
- How to treat symptoms of strongyloidiasis in Vietnam?
- What is the follow-up after treatment for intestinal strongyloidiasis (Strongyloidiasis) in Vietnam?
What is the treatment principle for intestinal strongyloidiasis (Strongyloidiasis) in Vietnam?
Under the provisions of sub-section 5.1, Section 5, Guidance, issued together with Decision 1384 / QD-BYT in 2022 guiding the diagnosis, treatment and prevention of strongyloidiasis, issued by the Minister of Health, regulates the Treatment of intestinal strongyloidiasis is as follows:
- Treat with specific drugs to kill strongyloidiasis such as ivermectin, albendazole, thiabendazole.
- Symptomatic treatment with antihistamines, anti-digestive disorders, pain relief, ...
- Stop or reduce immunosuppressive therapy (if any).
- Improve physical condition and treat associated diseases.
The Ministry of Health guides the treatment of intestinal Strongyloidiasis in Vietnam: Contraindications to Albendazole for pregnant women in the first 3 months?
Guidelines for specific treatment of strongyloidiasis in Vietnam in 2022?
In sub-section 5.2, Section 5, Guidance issued together with Decision 1384 / QD-BYT of 2022 guiding the diagnosis, treatment and prevention of strongyloidiasis, issued by the Minister of Health, regulates the specific treatment of helminthiasis. Intestinal eels are as follows:
Use one of the following regimens
Regimen 1: Ivermectin 3mg, 6mg tablets
(1) Dosage
- Common form: children over 15kg and adults: 0.2 mg / kg of weight, use in 1-2 days, take 2 hours from meals.
- Type of serious disease, spread of strongyloidiasis: Dosage: 0.2mg / kg / day. drink until the stool and sputum test no longer see the strongyloidiasis, can be treated within 2 weeks.
(2) Contraindications
- Patients with known hypersensitivity to any ingredient of the drug.
- Patients with diseases associated with blood brain barrier disorder and meningitis.
- Children under 5 years old or body weight <15kg
- Pregnant and lactating women.
Regimen 2: Albendazole tablets 400 mg or 200 mg
(1) Dosage
- Common diseases:
+ Adults: 400mg / time X 2 times / day for 7 consecutive days.
+ Children> 2 years old: 400mg / time / day for 3 consecutive days.
+ Children <2 years old: 200mg / time / day for 3 consecutive days, can be repeated after 3 weeks.
- The form of serious disease, diffuse strongyloidiasis has complications using a dose of 400mg / time X 2 times / day for 7 days. Follow-up test of strongyloid larvae in 2-4 weeks, if the larvae remain, the dose is continued as before.
(2) Contraindications
- Having a history of hypersensitivity to the compounds of the benzimidazol type or to certain ingredients of the drug.
- Patients with a history of bone marrow toxicity.
- Women who are pregnant in the first 3 months or are breastfeeding.
- Children under 2 years old.
Regimen 3: Thiabendazol 500 mg tablet
(1) Dosage: 25mg / kg / time X 2 times / day (maximum 3g / day). drink after eating.
- For the normal form: 2-day treatment.
- For diffuse strongyloidiasis: treatment lasts a minimum of 5-7 days or until the larvae are cleared.
(2) Contraindications
- In cases of hypersensitivity to any ingredient of the drug.
- Pregnant and lactating women.
- Pediatric patients weighing less than 13.6 kg.
How to treat symptoms of strongyloidiasis in Vietnam?
In sub-section 5.3, Section 5, Guidance issued together with Decision 1384 / QD-BYT of 2022 guiding the diagnosis, treatment and prevention of strongyloidiasis, issued by the Minister of Health, regulates symptomatic treatment of the disease. intestinal strongyloidiasis is:
- Improve fitness, have a reasonable diet and rest.
- If the patient has diarrhea and diarrhea, it is necessary to be treated with infusion to rehydrate and electrolytes.
- If there is an infection, it must be treated with antibiotics.
- There are signs of itching must use antihistamines.
- Treatment of accompanying diseases.
What is the follow-up after treatment for intestinal strongyloidiasis (Strongyloidiasis) in Vietnam?
The follow-up after treatment of intestinal strongyloidiasis is specified in subsection 5.4, Section 5, Guidance issued together with Decision 1384 / QD-BYT in 2022 guiding the diagnosis, treatment and prevention of strongyloidiasis. The Minister of Health promulgates specifically as follows:
- Monitoring of inpatient treatment:
+ The patient is monitored at an inpatient facility for about 7 days.
+ Retest stool in 3 days on Thursday, 6th, 7th during inpatient treatment, blood count test, biochemistry of liver and kidney function to evaluate organ function of the body.
+ For patients with underlying diseases, do tests to monitor and treat related underlying diseases.
- Follow-up after inpatient treatment:
The indicators evaluate the effectiveness of treatment, after the treatment period of 1 month, 3 months, 6 months and 12 months.
+ Clinical: clinical symptoms decrease or disappear
+ Test the stool or duodenal fluid or sputum without strongyloid larvae
+ Complete blood count: the number of eosinophils returned to normal or decreased
+ Biochemistry: liver, kidney function
+ Strongyloid ELISA, IgE reevaluated after 3 months, 6 months, 12 months and longer if still positive.
+ Ultrasound of the abdomen: the loops of the small intestine return to normal.
+ CT scan, MRI of the brain: the damage is reduced or gone.
Above is some of the information we provide to you. Best regards!
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