Favipiravir treatment for F0 with mild and moderate COVID-19 infections in Vietnam

According to the latest guidance from the Ministry of Health of Vietnam, the antiviral drug Favipiravir is now used to treat mild and moderate COVID-19 infections for 5-7 days, instead of treating only mild infection upto 7-14 days.


Favipiravir is used for treating F0 with mild and moderate COVID-19 infections.

Decision 5666/QĐ-BYT issued on December 12, 2021 on amendments to the guidelines for diagnostic testing and treating COVID-19 in Vietnam.

In particular, the Ministry of Health of Vietnam makes amendments to regulations on 3 types of antiviral drugs' indications, contraindications, and dosage used to treat COVID-19 as follows:

Favipiravir 200 mg is used to treat F0 with mild and moderate COVID-19 infections (according to Decision 4689/QĐ-BYT, this antiviral drug was only used to treat mild COVID-19 infections). The duration of Favipiravir 200mg treatment was reduced to 5-7 days (instead of 7-14 days as previously stipulated).

For Remdesivir, the duration of medical treatment  for COVID-19 patient is from 5-7 days (which was 5 days as previously stipulated)

For Molnupiravir, the indications, contraindications, and dosage are applied according to the clinical trial protocol development which was approved.

In addition, the Ministry of Health of Vietnam also clearly states the principles for antiviral drug treatment as follows:

- Treatment using drugs that have not been recommended by WHO, or have not been licensed for circulation, or have not been licensed for emergency use in any country in the world,... must follow the regulations on clinical trials of the Ministry of Health.

- Treatment using drugs recommended by WHO, or licensed for circulation, or licensed for emergency use in at least 1 country in the world..., may be applied based on the patient's condition (e.g., Remdesivir, Favipiravir...).

Decision 5666/QD-BYT takes effect from 12/12/2021.

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